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We have 22 hotels in Mytilene.

Pyrgos of Mytilene Star Rating 4        
49 El. Venizelou Street

Built in 1916, this refined upscale hotel with a 3-story turret is 2 km from the bronze Agalma Tis Eleftherias statue at the Port of Myteline in the Aegean Sea.Featuring gilded furniture designed to evoke the style of 18th-century France, the 12 plush, individually decorated rooms offer minibars, satellite TV and free Wi-Fi, plus garden, city or sea views. Some add exposed-stone walls and/or balconies.
Theofilos Paradise Boutique Hotel Star Rating 4        
7 Skra Street, Hatzidimou Park

Set in a traditional mansion house, this elegant hotel is a 1-minute walk from the harbor and 12 minutes' walk from both the Archaeological Museum of Mytilene and the Yeni Mosque.Decorated in warm earth tones, the chic rooms come with free Wi-Fi, air-conditioning and flat-screen TVs. They also include private bathrooms; 1 attic suite adds a sitting room.
Porto Lesvos I Star Rating 4        
Komninaki 21

Located a short walk from Mytilini Long Distance Bus Station, Porto Lesvos I is a convenient base when in Mytilene. It is also a short walk from the Archaeological Museum of Mytilene, University of the Aegean and Aegean University, and is close to many of the area's popular attractions.The hotel has 12 rooms that are fitted with all the necessities to ensure a comfortable stay.
New Life Rooms        
Olympou 7

This Mytilene hotel is located within a 10-minute stroll of Mytilini Long Distance Bus Station. It is situated a short walk from the Archaeological Museum of Mytilene, University of the Aegean and Port of Mytilene.New Life Rooms offers cosy rooms, equipped to suit the requirements of any traveller.
Blue Sea Hotel Mytilene Star Rating 3        
91 P. Kountourioti Street

The BLUE SEA is a B' Class Hotel with 59 luxuriously furnished rooms. It has been fully renovated. It operates all year around.
Hotel Lesvion Star Rating 3        
27a P Koudourioti Street

Hotel Lesvion is located in the heart of Lesvos Town, only half a mile (one km) from the picturesque harbour and 4.3 miles (7 km) from the airport.Lesvion offers sound proofed guestrooms with internet access and a friendly service available 24 hours a day.
Hotel Sappho Star Rating 1        
P. Kountourioti 31

Overlooking the Port of Mytilene, this modest, waterfront hotel is a minute's walk from the nearest bus stop, a 10-minute walk from the Yeni Mosque, and an 11-minute walk from the renowned Statue of Liberty.Low-key rooms feature free Wi-Fi, TVs, minifridges and balconies; some have sea views. Room service is on offer.
Aklidi Hotel Star Rating 2        
26, Evagelistrias Street

Aklidi Hotel lies in a verdurous setting, only 150 yards from the sea and 0.9 miles from the centre of Mitilene. Open year-round, it offers accommodation with side sea views.
Olympias Boutique Hotel Star Rating 3        
3 E. Vostani Street

A great choice for a stay in Lesvos, Olympias Boutique Hotel is just 4.5 mi (7.2 km) from the airport.
Orfeas Hotel Star Rating 3        
3 Katsakouli Street

In a low-key residential neighborhood, this bright hotel beside the Archaeological Museum of Mytilene is a 4-minute walk from the closest beach and 10 minutes' walk from the Castle of Mytilene.Simple rooms with plain decor offer TVs, minifridges and complimentary Wi-Fi; most come with balconies and/or Aegean Sea views. Room service is available.
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Mytilene is an ancient city founded in the 11th century BC. Mytilene is the capital and port of the island of Lesbos and also the capital of the North Aegean Region. The seat of governor of the North Aegean Region is Mytilene.