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We have 3 hotels in Santiago Tuxtla.

Hotel Gran Santiago Plaza Confort Star Rating 4        
Esquina 5 de Mayo y Comonfort

This straightforward hotel with a cylindrical tower is a 5-minute walk from the nearest bus stop, 1.3 km from Cascada El Palenque waterfall and 22 km from the Laguna el Apompal.The unassuming rooms feature free Wi-Fi, cable TV and minibars.
Meson de Santiago Star Rating 3        
5 De Mayo No. 8 Col. Centro

Featuring free WiFi, an outdoor pool and a terrace, Meson de Santiago offers pet-friendly accommodation in Santiago Tuxtla. Free private parking is available on site.Each room includes a TV.
Estancia Olmeca        
Carr. Nacional Veracruz Minatitlan No 78 Col. Centro

Estancia Olmeca offers a comfortable setting when in Santiago Tuxtla.There are 10 rooms at the hotel, each offering all the necessities to ensure a comfortable stay..
More on Santiago Tuxtla .
Santiago Tuxtla is a small city and municipality in the Los Tuxtlas region of southern Veracruz, Mexico. The area was originally part of lands granted to Hernán Cortés by the Spanish Crown in 1531.