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We have 1 hotel in South Houston.

Palace Inn Spencer Highway Star Rating 3        
1622 Spencer Hwy

On a wide street lined with casual eateries, this budget airport hotel is 5 miles from William P. Hobby Airport and 14 miles from Downtown.Unfussy rooms have colorful decor, and come with free Internet access, and flat-screen TVs with premium channels, plus microwaves and minifridges.
More on South Houston .
South Houston is a city in the U.S. state of Texas, within Houston - The Woodlands - Sugar Land metropolitan area and Harris County. It is bordered by the cities of Houston and Pasadena.