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We have 10 hotels in Sikeston.

Country Hearth Inn Sikeston Star Rating 1        
100 Matthews Lane

Straightforward option featuring humble rooms, plus free continental breakfast & Wi-Fi...
Holiday Inn Express Sikeston Star Rating 2        
120 S Interstate Dr

Off Interstate 55, this straightforward lodging is 3.6 miles from the local culture at the Sikeston Depot Museum, 3.2 miles from Sikeston Memorial Airport, and 4.
Pear Tree Inn Sikeston Star Rating 2        
2602 Rear East Malone

Off Interstate 55, this straightforward hotel is a 3-minute walk from Sikeston Factory Outlet Stores, 2.6 miles from the Jaycee Bootheel Rodeo grounds and 3 miles from downtown Sikeston.The simply furnished rooms have free WiFi and cable TV, as well as coffeemakers, microwaves and minifridges.
Super 8 Sikeston Miner Star Rating 2        
2609 E Malone

This straightforward budget hotel is across the street from Miner Convention Center and Sikeston Memorial Airport, adjacent to Interstate 55 and a 7-minute drive from Jaycee Bootheel Rodeo.All rooms include en suite bathrooms and flat-screen TVs with premium cable or satellite channels, plus free WiFi. Kids 17 and under stay free with an adult.
Americas Best Value Inn & Suites Sikeston Star Rating 2        
220 S Interstate Drive

This simple all-suite hotel off Interstate 55 freeway is an 18-minute walk from Sikeston Factory Outlet Stores and 2.2 miles from Sikeston Bowling Center and Pro.The straightforward suites include free WiFi and TVs with premium cable channels, plus microwaves, minifridges and coffeemakers.
Motel 6 Sikeston Star Rating 1        
110 S. Interstate Drive I-55 at US-62/East Malone Street, Exit #67

This Motel 6 offers a wide variety of amenities including: 24-hour front desk service, facilities for persons with disabilities and complimentary coffee. For a nominal charge fax services are available. Snack, beverage and ice centers are available.
Drury Inn & Suites - Sikeston Star Rating 3        
2608 East Malone Ave.

Off I-94, this traditional hotel is a minute's walk from the Sikeston Factory Outlet Stores, 3 miles from the Sikeston Depot Museum and 6 miles from the Sikeston Regional Campus at Southeast Missouri State University.Featuring complimentary Wi-Fi, the warmly decorated rooms and suites also have flat-screen TVs, minifridges, microwaves and coffeemakers. Suites add separate living areas with pull-out sofas.
Holiday Inn Express & Suites Sikeston Southwest Star Rating 2        
115 Hospitality Drive

Near the intersection of Highways 60 and 62, this straightforward budget hotel is 2 miles from downtown Sikeston and 3 miles from Sikeston Memorial Airport.Featuring free Wi-Fi, the modern rooms and suites also have flat-screen TVs and microwaves, as well as minifridges and coffeemakers. Suites have sofabeds.
Sikeston Days Inn Star Rating 2        
1330 South Main Street

Off Highway 60, this simple hotel is 4.3 miles from Sikeston Factory Outlet Stores and 5 miles from Interstate 55.All rooms have en suite bathrooms with showers and tubs, plus free WiFi, TVs and coffeemakers.
Comfort Inn & Suites Sikeston Star Rating 2        
109 Matthews Lane

This straightforward hotel is 0.3 miles from Interstate 55, 3.1 miles from Sikeston and 3.
More on Sikeston .
Sikeston is a city located both in southern Scott County and northern New Madrid County, in the U.S. state of Missouri. It is situated just north of the "Missouri Bootheel", although many locals consider Sikeston a part of it.