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We have 4 hotels in Wilkesboro.

 
 
Holiday Inn Express in Wilkesboro Star Rating 3        
1700 Winkler Street

A 22-minute drive from Rendezvous Mountain Educational State Forest, this standard hotel is also a 2.1-mile drive from downtown Wilkesboro.The subdued rooms come with flat-screen TVs and desks, plus premium cable channels, coffeemakers and minifridges.
Hampton Inn Wilkesboro Star Rating 3        
1300 Collegiate Drive

This modern hotel set near the foothills of the Blue Ridge and Brushy mountains is 1.2 miles from downtown Wilkesboro, and 10.4 miles from Rendezvous Mountain Educational State Forest.
Red Carpet Inn Wilkesboro Star Rating 2        
1206 River Street

Simple hotel with straightforward rooms, plus a restaurant/lounge & swimming pool...
Graystone Manor of Wilkesboro Star Rating 2.5        
406 Woodland Blvd

Retreat to this 5000 Sq. Ft. English Stone Manor.
 
 
More on Wilkesboro .
 
Wilkesboro is a town in and the county seat of Wilkes County, North Carolina. The population was 3,413 at the 2010 census. The town is located along the south bank of the Yadkin River, directly opposite the town of North Wilkesboro.